Lin Wang
   Translational researcher
   University
Fields of Expertise:
-
POSITIONS
Assistant Professor (PI)

Peking University Health Science Center





BIOGRAPHY

A desirable small animal model is urgently needed for HEV study. Our lab mainly focuses on developing a small animal model that can recapitulate key clinical features of human HEV infections and investigate the potential host tropism determinants.

SCIENTIFIC TRAININGS & EDUCATION

POSITIONS
  • -
Assistant Professor (PI)

Peking University Health Science Center

KEY PUBLICATIONS | ALL PUBLICATIONS

An Immunocompetent Mongolian Gerbil Model for Hepatitis E Virus Genotype 1 Infection

Liu Tianxu, He Q, Yang X, Li Y, Yuan D, Lu Q, Tang T, Guan G, Zheng L, Zhang H, Xia C, Yin X, Wei G, Chen X, Lu F, Wang Lin*

Publication: Gastroenterology, 2024;167(4):750-763.e10


Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system

Liu Tianxu#, Li J#, Yin X, Lu F, Zhao H, Wang Lin*, Qin CF*

Publication: Gut . 2024:gutjnl-2024-332784


Immunocompromised rabbit model of chronic HEV reveals liver fibrosis and distinct efficacy of different vaccination strategies

He Q, Zhang F, Shu J, Li S, Liang Z, Du M, Liu X, Liu Tianxu, Li M, Yin X, Pan Q, Lu F*, Wang L*, Wang Lin*

Publication: Hepatology. 2022;76(3):788-802


Urine is a viral antigen reservoir in hepatitis E virus infection

Ying D#, He Q#, Tian W#, Chen Y#, Zhang X, Wang S, Liu C, Chen Z, Liu Y, Fu L, Yan L, Wang L, Tang Z*, Wang Lin*, Zheng Z*, Xia N*

Publication: Hepatology. 2023;77(5):1722-1734


Hepatitis E virus infection activates NOD-like receptor family pyrin domain-containing 3 inflammasome antagonizing interferon response but therapeutically targetable

Li Y, Yu P, Kessler AL, Shu J, Liu X, Liang Z, Liu J, Li Y, Li P, Wang L, Wang Y, Ma Z, Liu A, Wang L, Bruno MJ, de Man RA, Peppelenbosch MP, Buschow SI, Wang Lin*, Wang Y*, Pan Q*

Publication: Hepatology. 2022;75(1):196-212