Research Papers


All research highlights

Animal reservoir

Experimental model

Published by Kush Kumar Yadav, Scott Kenney

Hepatitis E virus (HEV) is traditionally regarded as a hepatotropic virus, but an increasing body of evidence has revealed its ability to infect tissues outside the liver. In recent years, detection o...


Virus-host interaction

Published by Kush Kumar Yadav, Scott Kenney, Xiang-Jin Meng

Hepatitis E virus (HEV), is a leading cause of viral hepatitis globally, and is associated with adverse outcomes during pregnancy. Despite its clinical significance, the mechanisms driving enhanced HE...


Virology

Published by Loan Dao Thi

The hepatitis E virus (HEV) capsid protein ORF2 is best known for its essential role in virion assembly. However, a new study by Jordan & Hu et al., led by Dr. Viet Loan Dao Thi, uncovers an unexp...


One health

Published by Luz Chacón

Recently, the first detection of hepatitis E virus (HEV) in wastewater in Costa Rica was reported, representing also the first environmental report of this virus in Central America. The study analy...


Pathology

Virus-host interaction

Published by Kuan Liu, Qiuwei Abdullah Pan

Viral infections in host cells generally follow two major patterns: lytic and nonlytic, which are fundamental to viral life cycles and pathogenesis. In a lytic infection, the virus rapidly replicates ...


Clinical feature

Public health

Published by Siddharth Sridhar, JIANWEN SITU

Rat hepatitis E virus (rHEV, Rocahepevirus ratti genotype 1) has recently emerged as a zoonotic pathogen. It has been detected in rat populations in several countries and regions, and accumulating cas...


Experimental model

Virus-host interaction

Published by Loan Dao Thi

The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide and is primarily transmitted via the fecal-oral route. While HEV replication has been extensively studied in hepatocytes...


Animal reservoir

Experimental model

Published by Lin Wang, Xin Yin

According to World Health Organization, hepatitis E virus (HEV) caused an estimated 19.47 million cases of acute hepatitis E (AHE) globally in 2021; HEV was responsible for 5.4% of global disability-a...


Virus-host interaction

Published by Yijin Wang, 小曼 刘

Hepatitis E virus (HEV) is a major cause of acute hepatitis globally, yet the mechanisms underlying its replication and pathogenesis remain poorly understood. While mitochondrial dynamics—the balanc...


Virus-host interaction

Published by Qiang Ding, Lin Wang

Hepatitis E virus (HEV) remains a major cause of acute viral hepatitis worldwide, with an estimated 20 million infections annually. Although infection is often self-limiting, severe disease occurs in ...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)