Experimental model
All relevant publications
Experimental model
Virus-host interaction
Published by
Loan Dao Thi
The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide and is primarily transmitted via the fecal-oral route. While HEV replication has been extensively studied in hepatocytes...
The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide and is primarily transmitted via the fecal-oral route. While HEV replication has been extensively studied in hepatocytes...
Animal reservoir
Experimental model
Published by
Lin Wang, Xin Yin
According to World Health Organization, hepatitis E virus (HEV) caused an estimated 19.47 million cases of acute hepatitis E (AHE) globally in 2021; HEV was responsible for 5.4% of global disability-a...
According to World Health Organization, hepatitis E virus (HEV) caused an estimated 19.47 million cases of acute hepatitis E (AHE) globally in 2021; HEV was responsible for 5.4% of global disability-a...
Experimental model
Published by
Lin Wang
Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, belongs to the Hepeviridae family and is the causative agent of hepatitis E. HEV is distributed worldwide and is most prevalent in ...
Hepatitis E virus (HEV), a single-stranded positive-sense RNA virus, belongs to the Hepeviridae family and is the causative agent of hepatitis E. HEV is distributed worldwide and is most prevalent in ...
Experimental model
Virus-host interaction
Published by
Kuan Liu, Pengfei Li, Qiuwei Abdullah Pan
Severe acute viral diseases, such as cute hepatitis E caused by HEV infection, have prominent features of pathological inflammation that leads to tissue damage in patients. Macrophages have been recog...
Severe acute viral diseases, such as cute hepatitis E caused by HEV infection, have prominent features of pathological inflammation that leads to tissue damage in patients. Macrophages have been recog...
Experimental model
Virus-host interaction
Published by
Debin Tian, Xiang-Jin Meng
Hepatitis E virus genotype 1 (HEV-1) infection in pregnant women is associated with adverse outcomes of pregnancy including fulminant hepatic failure, fetal loss, premature birth and neonatal mortalit...
Hepatitis E virus genotype 1 (HEV-1) infection in pregnant women is associated with adverse outcomes of pregnancy including fulminant hepatic failure, fetal loss, premature birth and neonatal mortalit...
Experimental model
Virus-host interaction
Published by
Eike Steinmann
Hepatitis E virus (HEV) primarily causes liver infections, but emerging evidence suggests that it can also affect other organs, including the nervous system, leading to a range of neurological disorde...
Hepatitis E virus (HEV) primarily causes liver infections, but emerging evidence suggests that it can also affect other organs, including the nervous system, leading to a range of neurological disorde...
Experimental model
Published by
Lin Wang
The rapid establishment of a viral infection animal model is valuable for pathogenesis studies and testing of vaccines and therapeutic agents. Common approaches may require inoculation of experimental...
The rapid establishment of a viral infection animal model is valuable for pathogenesis studies and testing of vaccines and therapeutic agents. Common approaches may require inoculation of experimental...
Experimental model
Immunity
Published by
Qiyu He, Lin Wang
Chronic hepatitis E mostly occurs in organ transplant recipients and can lead to rapid liver fibrosis and cirrhosis. Previous studies found that the development of chronic hepatitis E virus (HEV) infe...
Chronic hepatitis E mostly occurs in organ transplant recipients and can lead to rapid liver fibrosis and cirrhosis. Previous studies found that the development of chronic hepatitis E virus (HEV) infe...
Experimental model
Published by
Lin Wang, tianxu liu
Viral hepatitis caused by hepatitis A, B, C, D and E viruses (HAV to HEV) is of great concern worldwide because of the associated burden of illness and death. However, immunocompetent small animal mod...
Viral hepatitis caused by hepatitis A, B, C, D and E viruses (HAV to HEV) is of great concern worldwide because of the associated burden of illness and death. However, immunocompetent small animal mod...
Experimental model
Published by
Siddharth Sridhar
Convenient small animal models of chronic hepatitis E are necessary for investigating the course of HEV infection in immunocompromised persons. Currently available small animal models for this purpose...
Convenient small animal models of chronic hepatitis E are necessary for investigating the course of HEV infection in immunocompromised persons. Currently available small animal models for this purpose...
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EVENTS
2025-01-18
International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)
