Virology


All relevant publications

Diagnostics

Virology

Published by Siddharth Sridhar, JIANWEN SITU

Human cases of Rocahepevirus ratti (HEV-C1) infection are increasingly reported worldwide. Serological tests for HEV-C1 infection are necessary for measuring the clinical burden of HEV-C1 on communiti...


Virology

Virus-host interaction

Published by Morgan Herod

Hepatitis E virus (HEV) is a common cause of acute viral hepatitis (inflammation of the liver). Although the infection usually self-resolves in healthy people, occasionally it can lead to acute liver ...


Virology

Published by Qiang Ding, Xiaohui Ju

Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis in the world. There are no direct-acting antivirals for HEV treatment. The mechanism of HEV replication, especially host facto...


Virology

Published by Zongdi Feng, Arash Grakoui

HEV has a single capsid protein encoded by its open reading frame (ORF) 2. Recent studies have shown that most of the ORF2 protein found in the circulation of HEV-infected patients is not associated w...


Virology

Published by Bo Wang, Xiang-Jin Meng

Hepatitis E virus (HEV) causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. Ribavirin (RBV) is the main therapeutic option for chronic hepatitis E as an off-lab...


Virology

Published by Thibault Tubiana, Sonia FIEULAINE, Stéphane Bressanelli

Structural biology, the field that produces atomic-level structures of biomacromolecules, has undergone several revolutions in the last ten years. The latest, and possibly the most far-reaching, is th...


Virology

Published by Laurence Cocquerel, Cyrine Bentaleb, Cécile-Marie Aliouat-Denis

Many gaps remain in the understanding of the Hepatitis E Virus (HEV) lifecycle. Notably, viral factories induced by HEV have not been documented yet and it is currently unknown whether HEV infection l...


Virology

Published by Laurence Cocquerel, Martin Ferrié, Maliki Ankavay

HEV genome expresses three open reading frames (ORFs): ORF1, ORF2 and ORF3. ORF1 encodes the ORF1 non-structural polyprotein that is the viral replicase. ORF2 encodes the ORF2 viral capsid protein and...


Virology

Published by Toni Lusie Meister, Eike Steinmann

Hepatitis E virus (HEV) has increasing prevalence worldwide with over three million infections every year. HEV is the causative agent of hepatitis E in humans and is the leading cause of enterically t...


Virology

Published by Bo Wang, Xiang-Jin Meng

Hepatitis E virus (HEV) infection in pregnant women has a high incidence of developing fulminant hepatic failure (FHF) with significant mortality. Multiple amino acid changes in the genome of HEV-1 ar...


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EVENTS

2023-04-28

2nd International HEV Symposium
The meeting will be held from April 28 to 29, 2023, in London. The 2-day meeting will feature talks and presentations given on the latest updates on HEV epidemiology, diagnostics, treatment, laboratory research, and disease control. More information: https://www.ivi.int/hev-symposium-2023/