At the beginning of April 2022 10 cases of severe acute hepatitis of unknown origin in children <10 years of age were reported across central Scotland. Rapidly, numbers increased with, thus far, 191 probable cases that have been identified across Europe, the United States of America, Israel and Japan. Until now, seventeen children required liver transplantation, one died. Accordingly, the Centers for Disease Control and Prevention and the European Centre for Diseases Prevention and Control have both issued a warning on a hepatitis of unknown origin in children. A recent review published in Journal of Hepatology focuses on the available information concerning this recent outbreak and introduces some of the discussed hypotheses for its development.
Read the full article “The recent outbreak of acute severe hepatitis in children of unknown origin – what is known so far”, online published in Journal of Hepatology, May 06, 2022.
Of note, original articles on the pathogenesis, the clinical course and the respective treatment options are most welcome for the Journal of Hepatology.
