Research Papers


All research highlights

Clinical feature

Treatment

Published by Maria Silva

Hepatitis E is a rising cause of acute hepatitis in developed nations. Most cases result in a mild and spontaneously cleared disease. Severe infections are characteristic of patients with previously e...


Prevention

Public health

Published by Heli Harvala

HEV and Blood Donation Hepatitis E virus (HEV) infections can have severe, even fatal implications for immunocompromised blood and platelet recipients. In England, all blood donations are screened ...


Clinical feature

Public health

Published by Peter Asaga Mac

HEV infection may be life-threatening in pregnant women and has been linked with 20–30% mortality, especially in the third trimester of pregnancy. HEV infection leads to elevated levels of preterm l...


Experimental model

Published by Siddharth Sridhar

Convenient small animal models of chronic hepatitis E are necessary for investigating the course of HEV infection in immunocompromised persons. Currently available small animal models for this purpose...


Public health

Published by Jose Debes

The hepatitis E virus (HEV) is an emergent causative agent of acute hepatitis worldwide, transmitted mainly by the fecal-oral route, which can progress to chronicity in immunosuppressed patients. HEV ...


Animal reservoir

One health

Published by Marina Meester

Hepatitis E virus (HEV) genotype 3 is very common in pig farms throughout the world and pigs are an important source of human infections in industrialized countries, probably mainly by consumption of ...


Virology

Published by Laurence Cocquerel, Martin Ferrié, Maliki Ankavay

HEV genome expresses three open reading frames (ORFs): ORF1, ORF2 and ORF3. ORF1 encodes the ORF1 non-structural polyprotein that is the viral replicase. ORF2 encodes the ORF2 viral capsid protein and...


Public health

Published by Abou Abdallah Malick DIOUARA

Hepatitis E is geographically a very heterogeneously distributed disease, being present in both developed and developing countries. Hepatitis E virus (HEV) transmission is essentially by the fecal–o...


Antiviral agent

Published by Mohammad Khalid Parvez

HEV has been recognized with eight genotypes (HEV1- HEV8), of which HEV1-HEV4 are infectious to humans. While HEV1 is waterborne infection causing self-limiting acute hepatitis E in general population...


Clinical feature

Published by Robert Fontana

Establishing a diagnosis of idiosyncratic drug induced liver injury (DILI) is challenging due to the need to exclude more common causes of acute liver injury such as viral hepatitis, pancreaticobiliar...


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EVENTS

2023-04-28

2nd International HEV Symposium
The meeting will be held from April 28 to 29, 2023, in London. The 2-day meeting will feature talks and presentations given on the latest updates on HEV epidemiology, diagnostics, treatment, laboratory research, and disease control. More information: https://www.ivi.int/hev-symposium-2023/