Research Papers


All research highlights

Public health

Published by Nishan Katuwal

HEV is estimated to cause approximately 20 million new infections annually, leading to around 3.3 million symptomatic cases and 70,000 deaths. However, these figures may be underestimated due to limit...


Pathology

Virus-host interaction

Published by -

Hepatitis E virus (HEV) is a widespread zoonotic pathogen and the leading cause of acute viral hepatitis globally. Recent studies have revealed that HEV infection is associated with a broad spectrum o...


Hepatology

Public health

Vaccine

Virology

Published by Susanne Dudman, Asma Aziz

We conducted a large phase 4, double-blind, cluster-randomised trial in 67 villages in Matlab, Bangladesh, and hereby share some of our results. Between 2017 and2021, 19 460 participants were randomis...


Clinical Trial

Prevention

Public health

Vaccine

Published by Asma Aziz

The safety of the HEV vaccine (Hecolin®) during or shortly before pregnancy remains uncertain, with only two studies from China providing limited insights. These studies had significant limitations s...


Animal reservoir

One health

Published by Kush Kumar Yadav, Scott Kenney

Rat HEV (Rocahepevirus ratti) is an emerging infectious disease with a global concern. Initial experiments in 2013 with rat HEV concluded it to be noninfectious to humans as evidenced by the absence o...


Vaccine

Published by Martin Eiden

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis globally. Currently, no causal treatment or universally licensed vaccine exists. Several recombinant HEV vaccines have been develope...


Public health

Published by Maria Belen Pisano

The hepatitis E virus (HEV, specie Paslahepevirus balayani) is responsible for a liver disease that affects ∼ 20 million people worldwide every year, especially in low- and middle-income countries w...


Experimental model

Immunity

Published by Qiyu He, Lin Wang

Chronic hepatitis E mostly occurs in organ transplant recipients and can lead to rapid liver fibrosis and cirrhosis. Previous studies found that the development of chronic hepatitis E virus (HEV) infe...


Virus-host interaction

Published by Yijin Wang

Hepatitis E virus (HEV) infection in pregnant women is associated with a wide spectrum of adverse consequences for both mother and fetus. The high mortality in this population appears to be associated...


Virus-host interaction

Published by Kush Kumar Yadav, Scott Kenney

Hepatitis E virus (HEV) is the leading cause of acute viral hepatitis globally. In the last few decades, HEV has been described as causing extrahepatic clinical manifestations including neurological, ...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)