Research Papers


All research highlights

Virus-host interaction

Published by Harini Sooryanarain, Xiang-Jin Meng

Hepatitis E virus (HEV) infection is usually a self-limiting disease with an overall case-fatality rate of less than 1%; however in pregnant women mortality rate can increase up to 20-30%. The exact m...


Diagnostics

Published by Jian Wu, Hongcui Cao

In the past decade, acute liver failure (ALF) caused by hepatitis E virus (HEV) infection has become more common, although HEV infection usually causes acute and self-limiting disease. However, there ...


Experimental model

Published by Loan Dao Thi

The heterogenous nature of hepatitis E virus (HEV) infections poses clinical challenges. Tropical HEV genotype (GT)1 & 2 infections can lead to acute liver failure, especially in pregnant women, w...


Virology

Published by Eike Steinmann

The hepatitis E virus (HEV) is the leading cause of acute viral hepatitis worldwide, affecting 20 million people per year. HEV-infections are self-limited, but can progress into fulminant or chronic h...


Diagnostics

Published by Jian Wu, Hongcui Cao

Hepatitis E is endemic in many developing countries, and hepatitis E virus is transmitted mainly by the fecal-oral route. It was estimated that approximately 20.1 million hepatitis E-related liver dis...


Experimental model

Published by Lin Wang

Hepatitis E virus (HEV) has become the emerging cause of viral hepatitis in humans worldwide with genotype 1-4 (HEV1-4) contributing to most cases in humans. Although most HEV infections are acute and...


Public health

Published by Eike Steinmann

The Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide and mainly transmitted via the fecal-oral route and/or consumption of contaminated food products. As a quasi-env...


Virus-host interaction

Published by Qiuwei Abdullah Pan, Yang Li

HEV infection caused liver diseases are closely related to dysregulation of immune responses, especially inflammatory response. Macrophages play a central role in immunosurveillance of the healthy liv...


Virus-host interaction

Published by , Qiuwei Abdullah Pan, Pengfei Li

Studying the biology of hepatitis E virus (HEV) infection and developing new therapeutics require robust experimental models. Although human liver cancer cell lines have been widely used to model HEV ...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)